⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048889 | 1.00 | — | — | |
| SCHEMBL9046191 | 1.00 | — | — | |
| SCHEMBL9821115 | 0.96 | ALDH1A1 (0.47) | — | |
| SCHEMBL45684 | 0.92 | — | — | |
| SCHEMBL9049423 | 0.92 | — | — | |
| SCHEMBL241045 | 0.84 | — | — | |
| SCHEMBL1775895 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL9047778 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL23203 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL7853217 | 0.81 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 309 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3921319-B1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEIGENE LTD (KY) | 2024-03-06 | — | — | EP | claimed |
| US-20230167117-A1 | IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEONE MEDICINES I GMBH (CH) | 2023-06-01 | — | — | US | claimed |
| EP-3921319-A1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BeiGene, Ltd. (KY) | 2021-12-15 | — | — | EP | claimed |
| CN-113423708-A | Imidazo [2,1-F ] [1,2,4] triazin-4-amine derivatives as TLR7 agonists | 百济神州有限公司 | 2021-09-21 | — | — | CN | claimed |
| WO-2020160710-A1 | IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST | BEIGENE, LTD. (KY) | 2020-08-13 | — | — | WO | claimed |
| EP-3126348-B1 | DIAMINOTRIAZINE COMPOUND USEFUL AS HERBICIDE | BASF SE (DE) | 2017-11-29 | — | — | EP | claimed |
| US-20170144985-A1 | DIAMINOTRIAZINE COMPOUND USEFUL AS HERBICIDE | BASF SE (DE) | 2017-05-25 | — | — | US | claimed |
| US-9650395-B2 | Antibacterial compounds and methods for use | PTC THERAPEUTICS, INC. (US) | 2017-05-16 | — | — | US | claimed |
| US-20170101383-A1 | DIAMINOTRIAZINE DERIVATIVES AS HERBICIDES | BASF SE (DE) | 2017-04-13 | — | — | US | claimed |
| EP-3126348-A1 | DIAMINOTRIAZINE COMPOUND USEFUL AS HERBICIDE | BASF SE (DE) | 2017-02-08 | — | — | EP | claimed |
| EP-0556310-B1 | QUINAZOLINES DERIVATIVES FOR ENHANCING ANTITUMOR ACTIVITY | PFIZER (US) | 1995-07-05 | — | — | EP | claimed |
| EP-0471236-B1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-03-15 | — | — | EP | claimed |
| EP-0556310-A1 | QUINAZOLINES DERIVATIVES FOR ENHANCING ANTITUMOR ACTIVITY. | PFIZER (US) | 1993-08-25 | — | — | EP | claimed |
| WO-1992007844-A1 | QUINAZOLINES DERIVATIVES FOR ENHANCING ANTITUMOR ACTIVITY | PFIZER INC. (US) | 1992-05-14 | — | — | WO | claimed |
| EP-0471236-A1 | Imidazopyridine derivatives and their use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-19 | — | — | EP | claimed |
| US-4820695-A | GRAMNEGATIVE BACTERIA | ELI LILLY AND COMPANY (US) | 1989-04-11 | — | — | US | claimed |
| US-4735959-A | HYPOGLYCEMIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1988-04-05 | — | — | US | claimed |
| EP-0063826-B1 | 2-AMINO-BENZOIC-ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS MEDICINES OR INTERMEDIATES | Dr. Karl Thomae GmbH (DE) | 1984-12-05 | — | — | EP | claimed |
| EP-0023569-B1 | DERIVATIVES OF CARBOXYLIC ACIDS, THEIR PREPARATION AND MEDICAMENTS CONTAINING THEM | Dr. Karl Thomae GmbH (DE) | 1983-06-22 | — | — | EP | claimed |
| EP-0023569-A1 | Derivatives of carboxylic acids, their preparation and medicaments containing them | Dr. Karl Thomae GmbH (DE) | 1981-02-11 | — | — | EP | claimed |