⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046191 | 0.84 | — | — | |
| SCHEMBL240836 | 0.84 | — | — | |
| SCHEMBL9048889 | 0.84 | — | — | |
| SCHEMBL9049423 | 0.84 | — | — | |
| SCHEMBL9821115 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL8062482 | 0.75 | GABRA1 (0.32) | — | |
| SCHEMBL7845053 | 0.73 | — | — | |
| SCHEMBL65274 | 0.73 | — | — | |
| SCHEMBL1224717 | 0.73 | — | — | |
| SCHEMBL677195 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 353 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247590-A1 | TRIAZOLOPYRIDINE AND BENZOISOXAZOLE CARBOXAMIDES AND THEIR USES AS PDGFR INHIBITORS | ACTELION PHARMACEUTICALS LTD (CH) | 2023-12-28 | — | — | WO | claimed |
| US-10695334-B2 | Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2020-06-30 | — | — | US | claimed |
| US-20200054617-A1 | Heteroaromatic Carboxamide Derivatives as Plasma Kallikrein Inhibitors | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2020-02-20 | — | — | US | claimed |
| US-10053434-B2 | Histone deacetylase inhibitors and compositions and methods of use thereof | CHDI FOUNDATION, INC. (US) | 2018-08-21 | — | — | US | claimed |
| EP-3303326-A1 | HETEROCYCLIC ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | H. Hoffnabb-La Roche Ag (CH) | 2018-04-11 | — | — | EP | claimed |
| EP-3291810-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI Foundation, Inc. (US) | 2018-03-14 | — | — | EP | claimed |
| EP-2852584-B1 | SUBSTITUTED DIPYRIDYLAMINES AND USES THEREOF | HOFFMANN LA ROCHE (CH) | 2018-02-28 | — | — | EP | claimed |
| EP-3205648-A1 | ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | Seragon Pharmaceuticals, Inc. (US) | 2017-08-16 | — | — | EP | claimed |
| WO-2016189011-A1 | HETEROCYCLIC ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | F. HOFFMANN-LA ROCHE AG (CH) | 2016-12-01 | — | — | WO | claimed |
| US-20160347742-A1 | HETEROCYCLIC ESTROGEN RECEPTOR MODULATORS AND USES THEREOF | GENENTECH, INC. (US) | 2016-12-01 | — | — | US | claimed |
| EP-0260555-A1 | Benzo-fused cycloalkane and oxa- and thia-, cycloalkane trans-1,2-diamine derivatives | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1988-03-23 | — | — | EP | claimed |
| EP-0224566-A1 | ANTIARRHYTHMIC USE FOR AMINOCYCLOALKYLAMIDES | THE UPJOHN COMPANY (US) | 1987-06-10 | — | — | EP | claimed |
| US-4632935-A | Omega-(hydroxy-, ether and ester)-alkyl-2-amino-cycloalkyl- and cycloalkenyl amides as analgesics | THE UPJOHN COMPANY (US) | 1986-12-30 | — | — | US | claimed |
| WO-1986007257-A2 | ANTIARRHYTHMIC USE FOR AMINOCYCLOALKYLAMIDES | THE UPJOHN COMPANY (US) | 1986-12-18 | — | — | WO | claimed |
| EP-0176309-A2 | Use of N-(2-aminocyclohexyl)benzeneacetamides in the treatment of cerebral ischemia | THE UPJOHN COMPANY (US) | 1986-04-02 | — | — | EP | claimed |
| EP-0167253-A1 | Hydroxyalkylcycloalkylbenzeneacetamides and benzamides | THE UPJOHN COMPANY (US) | 1986-01-08 | — | — | EP | claimed |
| US-4508911-A | Amine intermediates for analgesic compounds | THE UPJOHN COMPANY (US) | 1985-04-02 | — | — | US | claimed |
| EP-0129991-A1 | 2-Aminocycloalkenyl carboxamides and their tritiated 2-aminocycloalkyl carboxamide derivatives | THE UPJOHN COMPANY (US) | 1985-01-02 | — | — | EP | claimed |
| US-4463013-A | Oxygen substituted amino-cyclohexyl-benzeneacetamides and -benzamides as water diuretic drugs | THE UPJOHN COMPANY (US) | 1984-07-31 | — | — | US | claimed |
| US-4438130-A | Analgesic 1-oxa-, aza- and thia-spirocyclic compounds | THE UPJOHN COMPANY (US) | 1984-03-20 | — | — | US | claimed |