⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240836 | 1.00 | — | — | |
| SCHEMBL9046191 | 1.00 | — | — | |
| SCHEMBL9821115 | 0.96 | ALDH1A1 (0.47) | — | |
| SCHEMBL45684 | 0.92 | — | — | |
| SCHEMBL9049423 | 0.92 | — | — | |
| SCHEMBL241045 | 0.84 | — | — | |
| SCHEMBL1775895 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL9047778 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL23203 | 0.81 | ALDH1A1 (0.47) | — | |
| SCHEMBL7853217 | 0.81 | ALDH1A1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4325960-A | 6-Amidinopenicillanic acid derivatives including the radical of a β-lactamase inhibitor | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1982-04-20 | — | — | US | claimed |
| EP-0507534-B1 | Succinic acid compounds | KISSEI PHARMACEUTICAL (JP) | 1996-02-28 | — | — | EP | disclosed |
| US-5202335-A | Hypoglycemic, antidiabetic agents | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1993-04-13 | — | — | US | disclosed |
| EP-0507534-A1 | Succinic acid compounds | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1992-10-07 | — | — | EP | disclosed |
| US-4325960-A | 6-Amidinopenicillanic acid derivatives including the radical of a β-lactamase inhibitor | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB) (DK) | 1982-04-20 | — | — | US | disclosed |