Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.74 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1645158 | 0.92 | ALDH1A1 (0.58) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| SCHEMBL809349 | 0.89 | ALDH1A1 (0.82) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| SCHEMBL31532967 | 0.89 | ALDH1A1 (0.82) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL23882959 | 0.86 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL8690036 | 0.86 | ALDH1A1 (0.88) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL5668586 | 0.86 | ALDH1A1 (1.00) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL1686043 | 0.86 | ALDH1A1 (1.00) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL10477086 | 0.86 | ALDH1A1 (1.00) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL1332278 | 0.86 | ALDH1A1 (1.00) | ALDH1A1ALOX15AKR1C3KDM4ECA12 | |
| Phthalic Acid SCHEMBL146125 | 0.86 | ALDH1A1 (1.00) | ALDH1A1ALOX15AKR1C3KDM4ECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200263184-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CANCER, CONTAINING MALATE-ASPARTATE SHUTTLE INHIBITOR AND ANTICANCER DRUG AS ACTIVE INGREDIENTS | NATIONAL CANCER CENTER (KR) | 2020-08-20 | — | — | US | claimed |
| US-20200229571-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-KETO ACID DERIVATIVE | L'OREAL (FR) | 2020-07-23 | — | — | US | claimed |
| EP-3610866-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CANCER, CONTAINING MALATE-ASPARTATE SHUTTLE INHIBITOR AND ANTICANCER DRUG AS ACTIVE INGREDIENTS | National Cancer Center (KR) | 2020-02-19 | — | — | EP | claimed |
| EP-3141284-B1 | METHOD OF STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | OREAL (FR) | 2019-08-28 | — | — | EP | claimed |
| US-20190125051-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'OREAL (FR) | 2019-05-02 | — | — | US | claimed |
| EP-2029095-B1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | L'ORÉAL (FR) | 2017-08-30 | — | — | EP | claimed |
| US-20130139845-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | L'OREAL S.A. (FR) | 2013-06-06 | — | — | US | claimed |
| CN-103119208-A | A biocidal polyolefin yarn with 3-12 filaments | VESTERGAARD FRANDSEN SA | 2013-05-22 | — | — | CN | claimed |
| US-20100300471-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | L'OREAL S.A. (FR) | 2010-12-02 | — | — | US | claimed |
| CN-100416314-C | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL INC (US) | 2008-09-03 | — | — | CN | claimed |
| CN-1842730-A | Polarizing, photochromic devices and methods of making the same | TRANSITIONS OPTICAL INC (US) | 2006-10-04 | — | — | CN | claimed |
| EP-0219923-B1 | ANTIBIOTIC DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1992-09-02 | — | — | EP | claimed |
| US-4931509-A | EPOXY-CONTAINING MONOMER; EXCELLENT VULCANIZING WITH UREAS, QUATERNARY AMMONIUM AND PHOSPHONIUM SALTS AND POLYCARBOXYLIC ACIDS OR ANHYDRIDES | NIPPON ZEON CO., LTD. (JP) | 1990-06-05 | — | — | US | claimed |
| JP-55055168-A | — | — | None | — | — | JP | disclosed |
| JP-55043026-A | — | — | None | — | — | JP | disclosed |
| JP-55055169-A | — | — | None | — | — | JP | disclosed |
| JP-S5547678-A | NOVEL 2-PYRIDYL-1-PHTHALAZONE DERIVATIVE | ISHIKAWA MASAYUKI | 1980-04-04 | — | — | JP | disclosed |
| JP-S5543027-A | 2-PYRIDYL-1-PHTHALAZONE DERIVATIVE | ISHIKAWA MASAYUKI | 1980-03-26 | — | — | JP | disclosed |
| JP-S5543026-A | NOVEL 2-PHENYL-1-PHTHALAZONE DERIVATIVE | ISHIKAWA MASAYUKI | 1980-03-26 | — | — | JP | disclosed |
| US-4182876-A | ANTAGONIST FOR THROMBOXANE A2, USED IN TREATMENT OF CEREBRAL APOPLEXY AND MYOCARDIAL INFARCTION | MASAYUKI ISHIKAWA (JP) | 1980-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100300471-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | KRT18, KLK5, HOGA1 | ALDH1A1 347/4885ALOX15 1977/4885AKR1C3 67/4885 |
| US-20200229571-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-KETO ACID DERIVATIVE | KRT18, HOGA1, KHK | ALDH1A1 375/4885ALOX15 2006/4885AKR1C3 60/4885 |
| US-20200263184-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTING AND TREATING CANCER, CONTAINING MALATE-ASPARTATE SHUTTLE INHIBITOR AND ANTICANCER DRUG AS ACTIVE INGREDIENTS | SLC25A11, SLC16A1, MDH1 | ALDH1A1 714/4885ALOX15 2868/4885AKR1C3 1338/4885 |
| US-20190125051-A1 | PROCESS FOR STRAIGHTENING KERATIN FIBRES WITH A HEATING MEANS AND DENATURING AGENTS | KRT18, KRTCAP2, TUBB4A | ALDH1A1 2916/4885ALOX15 4688/4885AKR1C3 692/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.