Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.35 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 5/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412420 | 0.93 | GRM4 (0.38) | PTGDR2CCKARKAT6AKAT5HTR2C | |
| SCHEMBL2414740 | 0.91 | HTR2C (0.37) | RORCKAT6AKAT5HTR2CSLC6A4 | |
| SCHEMBL2409950 | 0.91 | HTR6 (0.38) | KAT6AKAT5HTR2CSLC6A4HTR2A | |
| SCHEMBL2415723 | 0.91 | HTR2C (0.39) | PTGDR2KAT6AKAT5HTR2CSLC6A4 | |
| SCHEMBL31187457 | 0.89 | KAT8 (0.35) | KAT6AKAT5HTR2CSLC6A4HTR2A | |
| SCHEMBL1278411 | 0.89 | KAT6A (0.34) | KAT6AKAT5HTR2CSLC6A4HTR2A | |
| SCHEMBL2409374 | 0.89 | HTR2C (0.40) | KAT6AKAT5HTR2CSLC6A4HTR2A | |
| SCHEMBL1278111 | 0.88 | RIPK1 (0.34) | PTGDR2KAT6AKAT5HTR2CSLC6A4 | |
| SCHEMBL2409152 | 0.88 | ALDH1A1 (0.37) | KAT6AKAT5HTR2CSLC6A4GAA | |
| SCHEMBL31187449 | 0.88 | MET (0.42) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |