Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4413097 | 0.94 | HTR2C (0.36) | HTR2CSLC6A4HTR2APOLBKAT6A | |
| SCHEMBL2414740 | 0.90 | HTR2C (0.37) | HTR2CSLC6A4HTR2AKAT6AKAT5 | |
| SCHEMBL2408620 | 0.90 | HTR2C (0.36) | HTR2CSLC6A4HTR2ARIPK1KAT6A | |
| SCHEMBL2409950 | 0.90 | HTR6 (0.38) | HTR2CSLC6A4HTR2ARIPK1KAT6A | |
| SCHEMBL2412876 | 0.89 | PTGDR2 (0.39) | HTR2CSLC6A4HTR2AKAT6AKAT5 | |
| SCHEMBL2412446 | 0.88 | POLB (0.37) | HTR2CHTR2APOLBRIPK1RXFP1 | |
| SCHEMBL2415723 | 0.88 | HTR2C (0.39) | HTR2CSLC6A4HTR2AKAT6AKAT5 | |
| SCHEMBL2415544 | 0.86 | NR3C2 (0.36) | HTR2CSLC6A4HTR2APOLBKAT6A | |
| SCHEMBL2412420 | 0.86 | GRM4 (0.38) | HTR2CSLC6A4HTR2AKAT6AKAT5 | |
| SCHEMBL1278111 | 0.85 | RIPK1 (0.34) | HTR2CSLC6A4RIPK1KAT6AKAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |