Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.38 |
| ▸ | HTR2C | P28335 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31187457 | 0.93 | KAT8 (0.35) | HTR6HTR2CHTR2AHTR7SLC6A4 | |
| SCHEMBL2415723 | 0.93 | HTR2C (0.39) | HTR6HTR2CHTR2ASLC6A4KAT8 | |
| SCHEMBL2414740 | 0.92 | HTR2C (0.37) | HTR6HTR2CHTR2ASLC6A4KAT8 | |
| SCHEMBL2409152 | 0.92 | ALDH1A1 (0.37) | HTR2CSLC6A4KAT8KAT6AKAT5 | |
| SCHEMBL31187449 | 0.92 | MET (0.42) | HTR6HTR2AALDH1A1HPGDDRD2 | |
| SCHEMBL1278111 | 0.91 | RIPK1 (0.34) | HTR2CSLC6A4RIPK1KAT8KAT6A | |
| SCHEMBL2412876 | 0.91 | PTGDR2 (0.39) | HTR2CHTR2ASLC6A4KAT8KAT6A | |
| SCHEMBL2414119 | 0.90 | RORC (0.37) | KAT8KAT6AKAT5 | |
| SCHEMBL2409374 | 0.90 | HTR2C (0.40) | HTR2CHTR2ASLC6A4RIPK1CPB2 | |
| SCHEMBL2412420 | 0.89 | GRM4 (0.38) | HTR2CHTR2ASLC6A4KAT8KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |