Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410849 | 0.88 | GABRA1 (0.49) | HPGDGABRA1GABRB2ALDH1A1MAPT | |
| SCHEMBL2412850 | 0.87 | HPGD (0.53) | HPGDGABRA1GABRB2ALDH1A1MAPT | |
| SCHEMBL2414418 | 0.87 | HPGD (0.49) | HPGDGABRA1GABRB2ALDH1A1 | |
| SCHEMBL2408990 | 0.87 | HPGD (0.56) | HPGDGABRA1GABRB2ALDH1A1MAPT | |
| SCHEMBL2410449 | 0.86 | RAB9A (0.49) | HPGDGABRA1GABRB2ALDH1A1MAPT | |
| SCHEMBL2413110 | 0.86 | GABRA1 (0.47) | HPGDGABRA1GABRB2ALDH1A1 | |
| SCHEMBL2416622 | 0.84 | GABRA1 (0.45) | HPGDGABRA1GABRB2ALDH1A1 | |
| SCHEMBL2413426 | 0.79 | NPC1 (0.46) | HPGDGABRA1GABRB2ALDH1A1 | |
| SCHEMBL6784969 | 0.75 | — | — | |
| SCHEMBL2410847 | 0.73 | GABRA1 (0.52) | HPGDGABRA1GABRB2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |
| EP-1828107-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | Sanofi-Aventis Deutschland GmbH (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063697-A1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-06-22 | — | — | WO | disclosed |