Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | HTR5A | P47898 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412850 | 0.93 | HPGD (0.53) | GABRA1GABRB2HTR5AHPGDALDH1A1 | |
| SCHEMBL2410849 | 0.91 | GABRA1 (0.49) | GABRA1GABRB2HTR5AHPGDALDH1A1 | |
| SCHEMBL2410449 | 0.89 | RAB9A (0.49) | GABRA1GABRB2HPGDALDH1A1 | |
| SCHEMBL2416622 | 0.87 | GABRA1 (0.45) | GABRA1GABRB2HPGDALDH1A1USP2 | |
| SCHEMBL2414418 | 0.86 | HPGD (0.49) | GABRA1GABRB2HTR5AHPGDALDH1A1 | |
| SCHEMBL2408993 | 0.86 | HPGD (0.53) | GABRA1GABRB2HPGDALDH1A1 | |
| SCHEMBL14015153 | 0.86 | GABRA1 (0.49) | GABRA1GABRB2HTR5AHPGDALDH1A1 | |
| SCHEMBL2415460 | 0.83 | ROCK1 (0.42) | — | |
| SCHEMBL2413426 | 0.82 | NPC1 (0.46) | GABRA1GABRB2HPGDALDH1A1USP2 | |
| SCHEMBL2411428 | 0.79 | LPAR1 (0.49) | HPGDALDH1A1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1828107-B1 | HYDROXYBIPHENYL CARBOXYLIC ACIDS AND DERIVATIVES, METHOD FOR PRODUCING THE SAME AND THEIR USE | SANOFI AVENTIS DEUTSCHLAND (DE) | 2011-09-28 | — | — | EP | disclosed |