Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24090254 | 0.82 | PRMT5 (0.58) | SMN1; SMN2CCR6PRMT5WDR77MAPT | |
| SCHEMBL2705788 | 0.81 | KDM4E (0.56) | SMN1; SMN2MAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL12876854 | 0.79 | ATP4A (0.49) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL25415867 | 0.77 | MAPT (0.66) | SMN1; SMN2MAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL25278857 | 0.77 | PKM (0.55) | MAPTMEN1KMT2AKDM4ELMNA | |
| SCHEMBL2221441 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2MAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL13484523 | 0.76 | DHODH (0.58) | SMN1; SMN2MAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL694852 | 0.75 | ALDH1A1 (0.56) | SMN1; SMN2CCR6MAPTALDH1A1RAB9A | |
| SCHEMBL5733736 | 0.75 | CDC7 (0.53) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL28928759 | 0.74 | ESR1 (0.49) | SMN1; SMN2MAPTALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210380546-A1 | VACCINE ADJUVANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2021-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210380546-A1 | VACCINE ADJUVANT | IFNG, TLR9, LY96 | SMN1; SMN2 2318/4885CCR6 753/4885PRMT5 4468/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.