Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 4/20 | 0.34 |
| ▸ | PLAU | P00749 | 4/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.31 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | XDH | P47989 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24610274 | 0.89 | HTR1D (0.32) | PLGPLAUNPC1TP53CYP1A2 | |
| SCHEMBL24094162 | 0.89 | CTDSP1 (0.39) | CHEK2NPC1TP53GAARAB9A | |
| SCHEMBL24094118 | 0.85 | PRMT5 (0.41) | CHEK2XDHCYP1A2GAARAB9A | |
| SCHEMBL24610309 | 0.84 | IKBKE (0.39) | CHEK2CYP1A2 | |
| SCHEMBL24094286 | 0.83 | IKBKE (0.36) | CHEK2TP53CYP1A2HSD17B10 | |
| SCHEMBL24610300 | 0.83 | JAK2 (0.34) | CHEK2 | |
| SCHEMBL22967237 | 0.81 | CYP1A2 (0.43) | CYP1A2HSD17B10 | |
| SCHEMBL24094240 | 0.79 | NPBWR1 (0.35) | NPC1TP53RAB9AHSD17B10 | |
| SCHEMBL22967060 | 0.79 | ADORA2A (0.41) | — | |
| SCHEMBL22967056 | 0.79 | ADORA2A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743420-B1 | HETEROCYCLYLAMINO-SUBSTITUTED TRIAZOLES AS MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | REDX PHARMA PLC (GB) | 2021-12-15 | — | — | EP | disclosed |