Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.32 |
| ▸ | HTR1B | P28222 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | HIPK2 | Q9H2X6 | 1/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 4/20 | 0.31 |
| ▸ | PLAU | P00749 | 4/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24094128 | 0.89 | PLG (0.34) | PLGPLAUNPC1TP53CYP1A2 | |
| SCHEMBL24094162 | 0.88 | CTDSP1 (0.39) | NPC1TP53GAARAB9AHSD17B10 | |
| SCHEMBL24094286 | 0.86 | IKBKE (0.36) | TP53CYP1A2HSD17B10 | |
| SCHEMBL24610309 | 0.85 | IKBKE (0.39) | CYP1A2 | |
| SCHEMBL24094118 | 0.83 | PRMT5 (0.41) | CYP1A2GAARAB9A | |
| SCHEMBL24610300 | 0.82 | JAK2 (0.34) | — | |
| SCHEMBL22967237 | 0.82 | CYP1A2 (0.43) | ROCK2CYP1A2HSD17B10 | |
| SCHEMBL24094240 | 0.79 | NPBWR1 (0.35) | NPC1TP53RAB9AHSD17B10 | |
| SCHEMBL22967056 | 0.76 | ADORA2A (0.39) | ROCK2 | |
| SCHEMBL22967060 | 0.76 | ADORA2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026834-A1 | HETEROCYCLYLAMINO-SUBSTITUTED TRIAZOLES AS MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | Redx Pharma Plc (GB) | 2022-07-13 | — | — | EP | disclosed |