Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24094162 | 0.84 | CTDSP1 (0.39) | RAB9ANPC1MAPTTP53SMN1; SMN2 | |
| SCHEMBL24094128 | 0.79 | PLG (0.34) | RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL24610274 | 0.79 | HTR1D (0.32) | RAB9ANPC1TP53HSD17B10 | |
| SCHEMBL24094118 | 0.79 | PRMT5 (0.41) | RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL24094175 | 0.76 | KMT2A (0.39) | RAB9ANPC1MAPTTP53HPGD | |
| SCHEMBL24094286 | 0.73 | IKBKE (0.36) | MAPTTP53SMN1; SMN2HSD17B10HPGD | |
| SCHEMBL24610300 | 0.73 | JAK2 (0.34) | SMN1; SMN2 | |
| SCHEMBL24610275 | 0.73 | ALDH1A1 (0.38) | TP53HSD17B10KDM4E | |
| SCHEMBL24610309 | 0.73 | IKBKE (0.39) | ATM | |
| SCHEMBL22967237 | 0.73 | CYP1A2 (0.43) | MAPTSMN1; SMN2HSD17B10HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3743420-B1 | HETEROCYCLYLAMINO-SUBSTITUTED TRIAZOLES AS MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | REDX PHARMA PLC (GB) | 2021-12-15 | — | — | EP | disclosed |