Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.32 |
| ▸ | ACACB | O00763 | 2/20 | 0.32 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24094286 | 0.85 | IKBKE (0.36) | JAK2SYKACACASMN1; SMN2CHEK2 | |
| SCHEMBL24610309 | 0.84 | IKBKE (0.39) | JAK2SYKACACACHEK2ACACB | |
| SCHEMBL24094128 | 0.83 | PLG (0.34) | CHEK2 | |
| SCHEMBL24094174 | 0.83 | ROCK1 (0.46) | SMN1; SMN2ROCK1 | |
| SCHEMBL24610274 | 0.82 | HTR1D (0.32) | — | |
| SCHEMBL24094162 | 0.82 | CTDSP1 (0.39) | SMN1; SMN2CHEK2 | |
| SCHEMBL22967237 | 0.81 | CYP1A2 (0.43) | SMN1; SMN2 | |
| SCHEMBL24094185 | 0.81 | ROCK1 (0.33) | SMN1; SMN2ROCK1 | |
| SCHEMBL22967056 | 0.79 | ADORA2A (0.39) | SMN1; SMN2ROCK1 | |
| SCHEMBL22967060 | 0.79 | ADORA2A (0.41) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4026834-A1 | HETEROCYCLYLAMINO-SUBSTITUTED TRIAZOLES AS MODULATORS OF RHO-ASSOCIATED PROTEIN KINASE | Redx Pharma Plc (GB) | 2022-07-13 | — | — | EP | disclosed |