Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 7/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 3/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.31 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1833792 | 0.91 | KAT6A (0.32) | MMP2MMP9MMP8MMP13KAT6A | |
| SCHEMBL2409079 | 0.89 | TAS2R14 (0.37) | OXTRAVPR2AVPR1AMMP2MMP9 | |
| SCHEMBL2411042 | 0.89 | HTR6 (0.33) | NAMPTRORCKAT6AKAT5HTR2C | |
| SCHEMBL2409441 | 0.88 | HTR2C (0.35) | MMP2MMP9MMP8MMP13KAT6A | |
| SCHEMBL2408854 | 0.87 | NFE2L2 (0.34) | OXTRMMP2MMP9MMP8MMP13 | |
| SCHEMBL2411540 | 0.86 | MET (0.41) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL1278688 | 0.86 | KAT6A (0.33) | OXTRAVPR2AVPR1AMMP2MMP9 | |
| SCHEMBL2413759 | 0.85 | RORC (0.36) | NAMPTRORCKAT6AKAT5HTR2C | |
| SCHEMBL1832149 | 0.85 | HTR2C (0.33) | NAMPTRORCKAT6AKAT5HTR2C | |
| SCHEMBL4570003 | 0.85 | TAS2R14 (0.35) | OXTRAVPR2AVPR1AMMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |