Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 10/20 | 0.34 |
| ▸ | USP1 | O94782 | 2/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24095622 | 0.76 | NPSR1 (0.40) | P2RX3USP1 | |
| SCHEMBL24095597 | 0.72 | P2RX7 (0.33) | USP1P2RX7 | |
| SCHEMBL24095631 | 0.72 | P2RX3 (0.37) | P2RX3USP1HTR4 | |
| SCHEMBL20656039 | 0.70 | ADORA3 (0.40) | — | |
| SCHEMBL20652805 | 0.70 | P2RX3 (0.39) | P2RX3KCNH2 | |
| SCHEMBL20656170 | 0.69 | P2RX3 (0.34) | P2RX3USP1HTR4 | |
| SCHEMBL24095632 | 0.67 | PDE5A (0.31) | P2RX3 | |
| SCHEMBL24095814 | 0.67 | MAPK1 (0.38) | P2RX3 | |
| SCHEMBL20656015 | 0.67 | CNR2 (0.34) | P2RX3 | |
| SCHEMBL18833638 | 0.66 | USP1 (0.38) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3652176-B1 | SUBSTITUTED XANTHINE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2021-12-15 | — | — | EP | disclosed |