Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24100344 | 0.92 | RXRA (0.55) | HPGDTSHRKMT2ARXRARXRB | |
| SCHEMBL24100196 | 0.91 | PLA2G7 (0.48) | HPGDTSHRKMT2ARXRARXRB | |
| SCHEMBL24099835 | 0.88 | HPGD (0.55) | HPGDTSHRKMT2AALDH1A1CNR2 | |
| SCHEMBL24099614 | 0.88 | AR (0.48) | HPGDTSHRKMT2ARXRARXRB | |
| SCHEMBL24100194 | 0.83 | AR (0.46) | HPGDTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL24100853 | 0.80 | RXRA (0.48) | HPGDTSHRKMT2ARXRARXRB | |
| SCHEMBL24099852 | 0.80 | HPGD (0.47) | HPGDTSHRKMT2AALDH1A1CNR2 | |
| SCHEMBL24099616 | 0.76 | HPGD (0.39) | HPGDTSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL18351224 | 0.72 | RXRA (0.47) | HPGDKMT2ARXRARXRBRXRG | |
| SCHEMBL12354846 | 0.72 | HPGD (0.80) | HPGDTSHRKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922247-A1 | 15-PGDH INHIBITOR | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-12-15 | — | — | EP | disclosed |