Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 6/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24100344 | 0.92 | RXRA (0.55) | PLA2G7HPGDTSHRCNR2RXRA | |
| SCHEMBL24100149 | 0.91 | HPGD (0.47) | PLA2G7HPGDTSHRCNR2RXRA | |
| SCHEMBL24099835 | 0.90 | HPGD (0.55) | PLA2G7HPGDTSHRCNR2ALDH1A1 | |
| SCHEMBL24099614 | 0.86 | AR (0.48) | PLA2G7HPGDTSHRRXRARXRB | |
| SCHEMBL24100194 | 0.81 | AR (0.46) | HPGDTSHRCNR2ALDH1A1CNR1 | |
| SCHEMBL24100853 | 0.80 | RXRA (0.48) | HPGDTSHRCNR2RXRARXRB | |
| SCHEMBL24099616 | 0.78 | HPGD (0.39) | PLA2G7HPGDTSHRCNR2ALDH1A1 | |
| SCHEMBL24099852 | 0.77 | HPGD (0.47) | PLA2G7HPGDTSHRCNR2ALDH1A1 | |
| SCHEMBL20059820 | 0.71 | HPGD (0.61) | PLA2G7HPGDTSHRCNR2ALDH1A1 | |
| SCHEMBL10838466 | 0.71 | HTT (0.43) | TSHRALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922247-A1 | 15-PGDH INHIBITOR | Kyorin Pharmaceutical Co., Ltd. (JP) | 2021-12-15 | — | — | EP | disclosed |