Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15247632 | 0.83 | ESR1 (0.48) | ESR1ADRB2ACHETSHRSOS1 | |
| SCHEMBL2402249 | 0.83 | SLC6A4 (0.50) | ESR1ADRB2ACHETSHRSOS1 | |
| SCHEMBL6114378 | 0.81 | ESR1 (0.46) | ESR1ADRB2ACHETSHRSOS1 | |
| SCHEMBL28879943 | 0.81 | ESR1 (0.46) | ESR1ADRB2ACHETSHRSOS1 | |
| SCHEMBL24105695 | 0.78 | ESR1 (0.48) | ESR1ADRB2ACHETSHRSOS1 | |
| SCHEMBL20365617 | 0.78 | ADRB2 (0.50) | ESR1ADRB2ACHETSHRSOS1 | |
| SCHEMBL16308854 | 0.78 | TDP1 (0.52) | ESR1ADRB2TSHRSOS1ACP3 | |
| SCHEMBL2332685 | 0.77 | ESR1 (0.52) | ESR1ACHETSHRACP3ALDH1A1 | |
| SCHEMBL143737 | 0.77 | ESR1 (0.52) | ESR1ACHETSHRACP3ALDH1A1 | |
| SCHEMBL3867592 | 0.77 | ESR1 (0.52) | ESR1ACHETSHRACP3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2663335-A1 | A COMPOSITION FOR THE REGENERATION OF ATROPHIC TISSUES | Medestea Internazionale S.p.A. (IT) | 2013-11-20 | — | — | EP | claimed |
| US-20130287757-A1 | COMPOSITION FOR THE REGENERATION OF ATROPHIC TISSUES | MEDESTEA INTERNAZIONALE S.P.A. (IT) | 2013-10-31 | — | — | US | claimed |
| WO-2012095702-A1 | A COMPOSITION FOR THE REGENERATION OF ATROPHIC TISSUES | MEDESTEA INTERNAZIONALE S.P.A. (IT) | 2012-07-19 | — | — | WO | claimed |
| EP-2663335-A1 | A COMPOSITION FOR THE REGENERATION OF ATROPHIC TISSUES | Medestea Internazionale S.p.A. (IT) | 2013-11-20 | — | — | EP | disclosed |
| US-20130287757-A1 | COMPOSITION FOR THE REGENERATION OF ATROPHIC TISSUES | MEDESTEA INTERNAZIONALE S.P.A. (IT) | 2013-10-31 | — | — | US | disclosed |
| WO-2012095702-A1 | A COMPOSITION FOR THE REGENERATION OF ATROPHIC TISSUES | MEDESTEA INTERNAZIONALE S.P.A. (IT) | 2012-07-19 | — | — | WO | disclosed |
| EP-0862550-A1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997009294-A1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-13 | — | — | WO | disclosed |
| EP-0263280-B1 | PROCESS FOR THE PREPARATION OF ELASTIC AND FLEXIBLE OPEN-CELL POLYURETHANE FOAMS HAVING AN ENHANCED STRAIN HARDNESS | BAYER AG (DE) | 1991-07-24 | — | — | EP | disclosed |
| EP-0369286-A2 | Dibenzozepine derivatives for treating acute and chronic obstructive diseases of the respiratory tract | Dr. Karl Thomae GmbH (DE) | 1990-05-23 | — | — | EP | disclosed |
| EP-0263280-A1 | Process for the preparation of elastic and flexible open-cell polyurethane foams having an enhanced strain hardness | BAYER AG (DE) | 1988-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130287757-A1 | COMPOSITION FOR THE REGENERATION OF ATROPHIC TISSUES | CUTA, UNG, MMP1 | ESR1 4153/4885ADRB2 814/4885ACHE 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.