SCHEMBL24107601

SCHEMBL24107601

CS(=O)(=O)N1CCN(c2ccc(C(=O)Nc3nc(Br)cs3)nc2)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.46
HTT P42858 1/20 0.46
MAPT P10636 6/20 0.44
NPC1 O15118 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
POLB P06746 1/20 0.42
KDM4E B2RXH2 2/20 0.41
HPGD P15428 1/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.40
ABL1 P00519 1/20 0.40
BCR P11274 1/20 0.40
LMNA P02545 1/20 0.40
THRB P10828 1/20 0.40
GRM5 P41594 1/20 0.40
HDAC3 O15379 1/20 0.40
TSHR P16473 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30263387 0.85 AOC3 (0.43) RAB9AMAPTNPC1MEN1KMT2A
SCHEMBL24107510 0.85 AOC3 (0.43) RAB9AMAPTNPC1MEN1KMT2A
SCHEMBL30292535 0.85 NFKB1 (0.45) RAB9AHTTMAPTNPC1SMN1; SMN2
SCHEMBL24107589 0.85 NFKB1 (0.45) RAB9AHTTMAPTNPC1SMN1; SMN2
SCHEMBL24107651 0.84 HDAC3 (0.40) RAB9AMAPTNPC1SMN1; SMN2KDM4E
SCHEMBL25770100 0.83 ALDH1A1 (0.44) RAB9AMAPTNPC1SMN1; SMN2MEN1
SCHEMBL24107778 0.83 HDAC3 (0.39) RAB9AHTTMAPTNPC1SMN1; SMN2
SCHEMBL24107779 0.83 CHRNB2 (0.50) ABL1HDAC3KCNH2
Hydrochloric Acid SCHEMBL25252917 0.82 CHRNB2 (0.49) ABL1HDAC3KCNH2
Hydrochloric Acid SCHEMBL30263441 0.82 CHRNB2 (0.49) ABL1HDAC3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230212131-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-07-06 US disclosed
US-20230212131-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-07-06 US disclosed
US-20230212131-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2023-07-06 US disclosed
EP-4161921-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF Anima Biotech Inc. (US) 2023-04-12 EP disclosed
CN-115916776-A Collagen 1 translation inhibitors and methods of use thereof 艾尼莫生物科技公司 2023-04-04 CN disclosed
WO-2021252555-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF ANIMA BIOTECH INC. (US) 2021-12-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212131-A1 COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF COL1A1, COL2A1, COL14A1 RAB9A 2752/4885HTT 3462/4885MAPT 3292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.