Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 2/20 | 0.39 |
| ▸ | ALPG | P10696 | 2/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.39 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | ARG1 | P05089 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3051709 | 0.84 | CA12 (0.60) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL14031929 | 0.79 | ALDH1A1 (0.59) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10364646 | 0.76 | MTNR1A (0.54) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10856186 | 0.76 | CA12 (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL27220883 | 0.75 | ALDH1A1 (0.67) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL812138 | 0.74 | ALDH1A1 (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3038961 | 0.74 | ALDH1A1 (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL10853038 | 0.74 | TMEM97 (0.51) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL3053615 | 0.74 | KMT2A (0.65) | CA12CA1CA2CA9ALDH1A1 | |
| Acetic Acid SCHEMBL14164721 | 0.73 | ALDH1A1 (0.80) | CA12CA1CA2CA9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12180318-B2 | Imidazolium zwitterion polymerizable compounds and ophthalmic devices incorporating them | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2024-12-31 | — | — | US | disclosed |
| WO-2021255551-A1 | IMIDAZOLIUM ZWITTERION POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES INCORPORATING THEM | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2021-12-23 | — | — | WO | disclosed |
| US-20210388141-A1 | IMIDAZOLIUM ZWITTERION POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES INCORPORATING THEM | JOHNSON & JOHNSON VISION CARE, INC. | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210388141-A1 | IMIDAZOLIUM ZWITTERION POLYMERIZABLE COMPOUNDS AND OPHTHALMIC DEVICES INCORPORATING THEM | ITPR3, RB1, ZW10 | CA12 3233/4885CA1 4070/4885CA2 962/4885 |
| US-12180318-B2 | Imidazolium zwitterion polymerizable compounds and ophthalmic devices incorporating them | ITPR3, ZW10, ITPR2 | CA12 3372/4885CA1 4216/4885CA2 921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.