Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2411710 | 0.83 | PRMT1 (0.68) | HDAC6HDAC8HDAC2MAPTKMT2A | |
| SCHEMBL2413993 | 0.81 | HDAC6 (0.58) | HDAC6HDAC8HDAC2MAPTLMNA | |
| SCHEMBL2410791 | 0.80 | HDAC6 (0.51) | HDAC6HDAC8HDAC2MAPTLMNA | |
| SCHEMBL2407780 | 0.76 | HDAC6 (0.52) | HDAC6HDAC8HDAC2MAPTKMT2A | |
| SCHEMBL2941910 | 0.73 | ALDH1A1 (0.59) | MAPTLMNAKMT2ANPSR1TBXA2R | |
| SCHEMBL2406521 | 0.72 | SLC1A3 (0.47) | HDAC6HDAC8MAPTLMNAKMT2A | |
| SCHEMBL14485055 | 0.72 | MAPT (0.80) | MAPTLMNAKMT2ATP53MEN1 | |
| SCHEMBL2408423 | 0.71 | HDAC8 (0.47) | HDAC6HDAC8HDAC2MAPTLMNA | |
| SCHEMBL10462381 | 0.71 | CYP1A2 (0.72) | MAPTKMT2AMEN1NPSR1CA1 | |
| SCHEMBL16404773 | 0.71 | HDAC6 (0.67) | HDAC6HDAC8HDAC2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |