Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 5/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 4/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.31 |
| ▸ | TUBB | P07437 | 3/20 | 0.31 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.31 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.31 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.31 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.31 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.31 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.31 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.31 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.31 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.31 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.31 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24110285 | 0.86 | HTR2A (0.33) | HTR2AHTR2CSMN1; SMN2 | |
| SCHEMBL24110306 | 0.86 | ACSS2 (0.33) | HTR2AHTR2C | |
| SCHEMBL24110300 | 0.85 | HTR2A (0.32) | HTR2AHTR2C | |
| SCHEMBL24110303 | 0.85 | NR3C1 (0.32) | HTR2AHTR2C | |
| SCHEMBL24109975 | 0.82 | FABP4 (0.39) | HTR2AHTR2C | |
| SCHEMBL24110255 | 0.78 | HTR2C (0.35) | TDO2AOC3HTR2CIDO1TUBB4A | |
| SCHEMBL24109718 | 0.78 | TNF (0.33) | HTR2AHTR2C | |
| SCHEMBL18247494 | 0.77 | TUBB4A (0.44) | CYP19A1NQO2TUBB4ATUBBTUBA3C | |
| SCHEMBL24110336 | 0.77 | NR3C1 (0.34) | HTR2AHTR2C | |
| SCHEMBL24109707 | 0.77 | KDM4E (0.38) | HTR2AHTR2CCYP19A1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| WO-2021252692-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | DELIX THERAPEUTICS, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230219969-A1 | ISOTRYPTAMINE PSYCHOPLASTOGENS AND USES THEREOF | GAP43, SLC18A2, PNMT | TDO2 1244/4885AOC3 1205/4885HTR2A 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.