Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20656251 | 0.84 | RAB9A (0.69) | RAB9ANPC1MAPTALDH1A1TDP1 | |
| SCHEMBL13113118 | 0.82 | LMNA (0.67) | RAB9ANPC1MAPTALDH1A1GAA | |
| SCHEMBL20977446 | 0.82 | KDM4E (0.64) | RAB9ANPC1MAPTALDH1A1TDP1 | |
| SCHEMBL24112442 | 0.82 | GAA (0.54) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL24112452 | 0.82 | LMNA (0.54) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL12733059 | 0.82 | HPGD (0.62) | RAB9ANPC1MAPTALDH1A1KMT2A | |
| SCHEMBL714886 | 0.82 | RAB9A (0.61) | RAB9ANPC1ALDH1A1TDP1KMT2A | |
| SCHEMBL206554 | 0.81 | TDP1 (0.61) | RAB9ANPC1MAPTALDH1A1TDP1 | |
| SCHEMBL1688854 | 0.81 | TDP1 (0.61) | RAB9ANPC1MAPTALDH1A1TDP1 | |
| SCHEMBL235800 | 0.81 | CA2 (0.73) | RAB9ANPC1MAPTALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001224-A1 | NOVEL COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF RENAL CANCERS | SHANGHAI MICURX PHARMACEUTICAL CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |
| WO-2021252644-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2021-12-16 | — | — | WO | disclosed |