Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 1.00 |
| ▸ | CHRM1 | P11229 | 4/20 | 1.00 |
| ▸ | CHRM3 | P20309 | 4/20 | 1.00 |
| ▸ | CHRM4 | P08173 | 1/20 | 1.00 |
| ▸ | CHRM5 | P08912 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinuclidinyl Benzilate SCHEMBL59698 | 1.00 | CHRM2 (1.00) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| Quinuclidinyl Benzilate SCHEMBL29433215 | 0.99 | CHRM2 (0.97) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9848226 | 0.93 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9145154 | 0.93 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9146007 | 0.93 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9148881 | 0.93 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL9146124 | 0.93 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL10814164 | 0.93 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL8529194 | 0.93 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 | |
| SCHEMBL10817618 | 0.93 | CHRM2 (0.86) | CHRM2CHRM1CHRM3CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240316023-A1 | BENEDIN, PIPERIDINE, 2-BENZHYDRYL-3-HYDROXY-N-METHYL-, HYDROCHLORIDE AND DERIVATIVES THEREOF FOR USE IN TREATING KLEINE-LEVIN SYNDROME | NLS PHARMACEUTICS AG (CH) | 2024-09-26 | — | — | US | disclosed |
| CN-117956994-A | Bei Niding, piperidine, 2-benzhydryl-3-hydroxy-N-methyl-, hydrochloride and derivatives thereof for the treatment of clariant-levensembles | NLS制药股份公司 | 2024-04-30 | — | — | CN | disclosed |
| EP-1633703-B1 | ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF | PERKINELMER LAS INC (US) | 2018-12-26 | — | — | EP | disclosed |
| US-8987501-B2 | Isotopically labeled chemically stable reagents and process for the synthesis thereof | PERKINELMER HEALTH SCIENCES, INC. (US) | 2015-03-24 | — | — | US | disclosed |
| US-20130030184-A1 | ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF | PERKINELMER HEALTH SCIENCES, INC. (US) | 2013-01-31 | — | — | US | disclosed |
| US-8329934-B2 | Isotopically labeled chemically stable reagents and process for the synthesis thereof | PERKINELMER HEALTH SCIENCES, INC. (US) | 2012-12-11 | — | — | US | disclosed |
| US-8168654-B2 | Quinuclidine derivatives binding to mucarinic M3 receptors | NOVARTIS AG (CH) | 2012-05-01 | — | — | US | disclosed |
| US-20120004413-A1 | ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF | PERKINELMER HEALTH SCIENCES, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| US-8058464-B2 | Isotopically labeled chemically stable reagents and process for the synthesis thereof | PERKINELMER HEALTH SCIENCES, INC. (US) | 2011-11-15 | — | — | US | disclosed |
| US-20100041887-A1 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | COLLINGWOOD STEPHEN PAUL | 2010-02-18 | — | — | US | disclosed |
| EP-1631569-B1 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | NOVARTIS AG (CH) | 2009-08-26 | — | — | EP | disclosed |
| US-20070060563-A1 | Quinuclidine derivatives binding to mucarinic m3 receptors | NOVARTIS AG (CH) | 2007-03-15 | — | — | US | disclosed |
| EP-1633703-A4 | ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF | PERKINELMER LAS INC (US) | 2006-11-15 | — | — | EP | disclosed |
| US-20060205953-A1 | Isotopically labeled chemically stable reagents and process for the synthesis thereof | PERKIN ELMER LAS, INC. (US) | 2006-09-14 | — | — | US | disclosed |
| EP-1633703-A2 | ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF | Perkinelmer Las, Inc. (US) | 2006-03-15 | — | — | EP | disclosed |
| EP-1631569-A2 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | Novartis AG (CH) | 2006-03-08 | — | — | EP | disclosed |
| WO-2004108636-A2 | ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF | PERKINELMER LAS, INC. (US) | 2004-12-16 | — | — | WO | disclosed |
| WO-2004096800-A2 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | NOVARTIS AG (CH) | 2004-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060563-A1 | Quinuclidine derivatives binding to mucarinic m3 receptors | CHRM3, CHRM2, CHRM1 | CHRM2 2/4885CHRM1 3/4885CHRM3 1/4885 |
| US-20240316023-A1 | BENEDIN, PIPERIDINE, 2-BENZHYDRYL-3-HYDROXY-N-METHYL-, HYDROCHLORIDE AND DERIVATIVES THEREOF FOR USE IN TREATING KLEINE-LEVIN SYNDROME | GABBR2, GABBR1, GABRB1 | CHRM2 950/4885CHRM1 887/4885CHRM3 1843/4885 |
| US-20130030184-A1 | ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF | ALKBH2, ALKBH3, ALKBH1 | CHRM2 1097/4885CHRM1 515/4885CHRM3 458/4885 |
| US-20120004413-A1 | ISOTOPICALLY LABELED CHEMICALLY STABLE REAGENTS AND PROCESS FOR THE SYNTHESIS THEREOF | HBG2, ALKBH2, ACVR2B | CHRM2 830/4885CHRM1 415/4885CHRM3 826/4885 |
| US-20100041887-A1 | QUINUCLIDINE DERIVATIVES BINDING TO MUCARINIC M3 RECEPTORS | CHRM3, CHRM2, CHRM1 | CHRM2 2/4885CHRM1 3/4885CHRM3 1/4885 |
| US-20060205953-A1 | Isotopically labeled chemically stable reagents and process for the synthesis thereof | MRPS23, MRPS22, IPO11 | CHRM2 1531/4885CHRM1 408/4885CHRM3 1013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.