SCHEMBL2411802

SCHEMBL2411802

O=C(N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(F)C(=O)C(F)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1)OCc1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ TACR1 P25103 2/20 0.66
▸ CTSL P07711 4/20 0.61
▸ CTSB P07858 3/20 0.61
▸ CTSS P25774 1/20 0.61
▸ CTSK P43235 1/20 0.61
▸ ALDH1A1 P00352 1/20 0.60
▸ ALOX15 P16050 1/20 0.60
▸ CAPN1 P07384 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7600777 0.89 CTSL (0.61) TACR1CTSLCTSBCTSSCTSK
SCHEMBL1264469 0.89 CTSL (0.61) TACR1CTSLCTSBCTSSCTSK
SCHEMBL2409535 0.87 CAPN1 (0.66) CTSLCTSBCTSSCTSKCAPN1
SCHEMBL30688477 0.85 TACR1 (0.70) TACR1CTSLCTSBCTSSCTSK
SCHEMBL30241933 0.85 TACR1 (0.70) TACR1CTSLCTSBCTSSCTSK
SCHEMBL16095807 0.85 TACR1 (0.70) TACR1CTSLCTSBCTSSCTSK
SCHEMBL8668091 0.85 TACR1 (0.70) TACR1CTSLCTSBCTSSCTSK
SCHEMBL8100557 0.85 TACR1 (0.70) TACR1CTSLCTSBCTSSCTSK
SCHEMBL12052836 0.85 TACR1 (0.70) TACR1CTSLCTSBCTSSCTSK
SCHEMBL10049956 0.85 TACR1 (0.70) TACR1CTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116157152-A Compositions and methods for improving the efficacy of a drug 赫利昂生物股份有限公司 2023-05-23 — — CN claimed
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO., INC. (US) 2023-05-11 — — US claimed
EP-4149552-A1 COMPOSITIONS AND METHODS FOR INCREASING EFFICACY OF A DRUG Healion Bio, Inc. (US) 2023-03-22 — — EP claimed
WO-2022072504-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES HEALION BIO, INC. (US) 2022-04-07 — — WO claimed
WO-2021231872-A1 COMPOSITIONS AND METHODS FOR INCREASING EFFICACY OF A DRUG HEALION BIO, INC. (US) 2021-11-18 — — WO claimed
US-8232240-B2 Inhibitors of enveloped virus infectivity THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2012-07-31 — — US claimed
EP-1827478-A4 METHODS OF TREATMENT FOR INJURED OR DISEASED JOINTS MUCOSAL THERAPEUTICS LLC (US) 2009-08-05 — — EP claimed
US-20090053263-A1 Inhibitors of Enveloped Virus Infectivity THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2009-02-26 — — US claimed
US-20080139458-A1 Lubricating a joint in a mammal by administering lubricin and an enzyme inhibitor like Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) MUCOSAL THERAPEUTICS 2008-06-12 — — US claimed
EP-1827478-A2 METHODS OF TREATMENT FOR INJURED OR DISEASED JOINTS Mucosal Therapeutics LLC (US) 2007-09-05 — — EP claimed
WO-2006091610-A2 INHIBITORS OF ENVELOPED VIRUS INFECTIVITY THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2006-08-31 — — WO claimed
WO-2006060473-A2 METHODS OF TREATMENT OF INJURED OR DISEASED JOINTS WITH LUBRICIN COMPOSITIONS MUCOSAL THERAPEUTICS LLC (US) 2006-06-08 — — WO claimed
CN-115066207-B Method and system for menstrual group analysis PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2026-05-26 — — CN disclosed
US-20240000949-A1 Nucleic Acid-Derivatized Therapeutics UNIV CHICAGO (US) 2024-01-04 — — US disclosed
US-20230257698-A1 FETAL TROPHOBLAST COMPOSITIONS AND METHODS NEXTGEN JANE, INC. 2023-08-17 — — US disclosed
CN-116367849-A Therapeutic agent derived from nucleic acid 芝加哥大学 2023-06-30 — — CN disclosed
US-20080139458-A1 Lubricating a joint in a mammal by administering lubricin and an enzyme inhibitor like Z-Leu-Leu-Leu-fluoromethyl ketone (Z-LLL-FMK) MUCOSAL THERAPEUTICS 2008-06-12 — — US disclosed
US-20070197438-A1 Dynamin mediated diseases and associated methods and products THE GENERAL HOSPITAL CORPORATION (US) 2007-08-23 — — US disclosed
WO-2007056435-A2 DYNAMIN MEDIATED DISEASES AND ASSOCIATED METHODS AND PRODUCTS THE GENERAL HOSPITAL CORPORATION (US) 2007-05-18 — — WO disclosed
WO-2006091610-A2 INHIBITORS OF ENVELOPED VIRUS INFECTIVITY THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) 2006-08-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230142126-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF VIRAL DISEASES CTSV, CTSB, CTSS TACR1 3337/4885CTSL 13/4885CTSB 2/4885
US-20240000949-A1 Nucleic Acid-Derivatized Therapeutics NSUN2, NSUN3, POLRMT TACR1 3829/4885CTSL 370/4885CTSB 502/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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