Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | NSD2 | O96028 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244041 | 0.82 | KDM1A (0.47) | KDM4CCACNA1BMEN1MAPTKMT2A | |
| SCHEMBL14821593 | 0.81 | CA12 (0.64) | KDM4CCACNA1BMEN1MAPTKMT2A | |
| SCHEMBL239798 | 0.76 | KDM4E (0.58) | KDM4CMEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL2870368 | 0.76 | LTA4H (0.43) | MAPTKMT2AALDH1A1HPGDTSHR | |
| SCHEMBL7566154 | 0.76 | L3MBTL1 (0.63) | KDM4CCACNA1BMEN1MAPTKMT2A | |
| SCHEMBL14542282 | 0.76 | ALDH1A1 (0.57) | KDM4CCACNA1BMAPTALDH1A1L3MBTL1 | |
| SCHEMBL13028245 | 0.73 | POLB (0.51) | KDM4CCACNA1BMEN1MAPTKMT2A | |
| SCHEMBL11215406 | 0.73 | CACNA1B (0.63) | CACNA1BHPGDL3MBTL1KDM4EADRA2C | |
| SCHEMBL7568020 | 0.72 | CACNA1B (0.47) | KDM4CCACNA1BMAPTALDH1A1HPGD | |
| SCHEMBL14284679 | 0.72 | L3MBTL1 (0.64) | MEN1MAPTKMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408451-A2 | RADIOLABELLED PYRIDINYL DERIVATIVES FOR IN-VIVO IMAGING | GE Healthcare UK Limited (GB) | 2012-01-25 | — | — | EP | disclosed |
| US-20120003154-A1 | ARYLOXYANILIDE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
| US-20120003154-A1 | ARYLOXYANILIDE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
| US-20120003154-A1 | ARYLOXYANILIDE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2012-01-05 | — | — | US | disclosed |
| WO-2010106166-A2 | ARYLOXYANILIDE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2010-09-23 | — | — | WO | disclosed |
| WO-2010106166-A2 | ARYLOXYANILIDE DERIVATIVES | GE HEALTHCARE LIMITED (GB) | 2010-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120003154-A1 | ARYLOXYANILIDE DERIVATIVES | GABBR1, GABRA4, CNR1 | KDM4C 1310/4885CACNA1B 1636/4885MEN1 3626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.