Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.50 |
| ▸ | ACP1 | P24666 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ASPH | Q12797 | 1/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11213118 | 0.90 | L3MBTL1 (0.58) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL14542280 | 0.88 | ABCB1 (0.62) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7569661 | 0.87 | APLNR (0.55) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7568812 | 0.87 | MAPK8 (0.60) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7570776 | 0.85 | MTNR1A (0.49) | L3MBTL1ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7568020 | 0.84 | CACNA1B (0.47) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL244041 | 0.82 | KDM1A (0.47) | L3MBTL1ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL14821593 | 0.81 | CA12 (0.64) | L3MBTL1ALDH1A1KDM4EMAPTGAA | |
| SCHEMBL14542282 | 0.81 | ALDH1A1 (0.57) | L3MBTL1ALDH1A1MAPTCACNA1BKDM4C | |
| SCHEMBL14542283 | 0.79 | ABCB1 (0.58) | ALDH1A1KDM4EGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476056-B2 | ANTIINFLAMMATORY AGENTS, PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2002-11-05 | — | — | US | disclosed |
| EP-1004573-B1 | ARYLOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO LTD (JP) | 2002-10-30 | — | — | EP | disclosed |
| US-20020147191-A1 | Aryloxyaniline derivatives | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-10-10 | — | — | US | disclosed |
| US-6333358-B1 | AMIDE DERIVATIVES OF ANILINE AS ANTIDEPRESSANTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2001-12-25 | — | — | US | disclosed |
| CN-1265642-A | Aryloxyaniline derivatives | TAISHO PHARMACEUTICAL CO LTD (JP) | 2000-09-06 | — | — | CN | disclosed |
| EP-1004573-A1 | ARYLOXYANILINE DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2000-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147191-A1 | Aryloxyaniline derivatives | FPR2, ARG2, CYP11B2 | L3MBTL1 3662/4885ALDH1A1 564/4885KDM4E 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.