SCHEMBL4632649

SCHEMBL4632649

O=C1C=CC(=O)N1c1ccc(S(=O)(=O)Nc2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.61
PKM P14618 4/20 0.61
MEN1 O00255 3/20 0.61
ALDH1A1 P00352 2/20 0.61
HSP90AA1 P07900 1/20 0.60
IL1RN P18510 1/20 0.59
KEAP1 Q14145 1/20 0.59
ERAP1 Q9NZ08 1/20 0.59
CA12 O43570 4/20 0.56
CA9 Q16790 4/20 0.56
CA2 P00918 3/20 0.56
CA1 P00915 2/20 0.56
HPGD P15428 1/20 0.54
MGLL Q99685 2/20 0.53
FAAH O00519 1/20 0.51
GAA P10253 1/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
MAPK1 P28482 1/20 0.50
HTT P42858 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24119970 0.78 MGLL (0.63) PKMALDH1A1HSP90AA1MGLLFAAH
SCHEMBL9001182 0.77 KMT2A (1.00) KMT2APKMMEN1ALDH1A1IL1RN
Phenyl(Phenylsulfonyl)Amine SCHEMBL114765 0.76 KEAP1 (1.00) KMT2APKMMEN1ALDH1A1IL1RN
SCHEMBL25031372 0.76 KEAP1 (1.00) KMT2APKMMEN1ALDH1A1IL1RN
SCHEMBL2626638 0.76 MGLL (0.56) PKMALDH1A1HSP90AA1CA12CA9
SCHEMBL571682 0.75 HSP90AA1 (1.00) KMT2APKMMEN1ALDH1A1HSP90AA1
SCHEMBL7463683 0.75 LMNA (0.72) KMT2APKMMEN1ALDH1A1IL1RN
SCHEMBL17369114 0.75 SMN1; SMN2 (0.63) KMT2APKMMEN1ALDH1A1IL1RN
SCHEMBL12549613 0.75 SMN1; SMN2 (0.63) KMT2APKMMEN1ALDH1A1IL1RN
SCHEMBL12549856 0.75 SMN1; SMN2 (0.63) KMT2APKMMEN1ALDH1A1IL1RN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1247820-B1 Method of preparing polymer particles having narrow particle size distribution AGFA GRAPHICS NV (BE) 2008-02-27 EP disclosed
US-6800709-B2 MONODISPERSE POLYMERS BY FREE RADICAL POLYMERIZATION OR COPOLYMERIZATION OF HYDROPHOBIC MONOMERS IN WATER-BASED SYSTEMS IN THE PRESENCE OF CYCLODEXTRIN AGFA-GEVAERT N.V. (BE) 2004-10-05 US disclosed
US-20020173610-A1 Method of preparing polymer particles having narrow particle size distribution AGFA GRAPHICS NV (BE) 2002-11-21 US disclosed
EP-1247820-A1 Method of preparing polymer particles having narrow particle size distribution Agfa-Gevaert (BE) 2002-10-09 EP disclosed