Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 3/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2412879 | 0.93 | PTGDR2 (0.43) | PTGDR2CCKARGRM4CNR1CNR2 | |
| SCHEMBL2414742 | 0.90 | PKM (0.35) | PTGDR2CCKARCNR1CNR2ALDH1A1 | |
| SCHEMBL2415727 | 0.90 | CHRM5 (0.37) | PTGDR2CCKARCNR1CNR2ALDH1A1 | |
| SCHEMBL1278414 | 0.89 | PTGDR2 (0.34) | PTGDR2CCKARCNR1CNR2ALDH1A1 | |
| SCHEMBL2418769 | 0.89 | HTR6 (0.37) | PTGDR2ALDH1A1NPSR1TSHR | |
| SCHEMBL5008567 | 0.87 | GRM4 (0.41) | PTGDR2CCKARGRM4CNR1CNR2 | |
| SCHEMBL1278112 | 0.86 | PTGER2 (0.36) | PTGDR2ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL4413582 | 0.86 | GRM4 (0.40) | PTGDR2CCKARGRM4CNR1CNR2 | |
| SCHEMBL2409158 | 0.86 | ALDH1A1 (0.40) | CRHBPCRHR2CNR1ALDH1A1LMNA | |
| SCHEMBL4413576 | 0.85 | GRM4 (0.40) | PTGDR2CCKARGRM4CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |