Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.32 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2415727 | 0.95 | CHRM5 (0.37) | PTGDR2GAACCKARHTR6CNR1 | |
| SCHEMBL2418769 | 0.92 | HTR6 (0.37) | PKMPTGDR2GAAHTR6CHRM5 | |
| SCHEMBL2412879 | 0.91 | PTGDR2 (0.43) | PTGDR2ALDH3A1GAACCKARHTR6 | |
| SCHEMBL1278414 | 0.91 | PTGDR2 (0.34) | PTGDR2CCKARCNR1CNR2L3MBTL1 | |
| SCHEMBL2409375 | 0.90 | POLB (0.35) | PKMPTGDR2CCKARHTR6 | |
| SCHEMBL2412424 | 0.90 | PTGDR2 (0.39) | PTGDR2CCKARCNR1CNR2ALDH1A1 | |
| SCHEMBL1278112 | 0.90 | PTGER2 (0.36) | PKMPTGDR2GAAALDH1A1 | |
| SCHEMBL1278691 | 0.88 | TAS2R14 (0.37) | PTGDR2CHRM5KMT2AALDH1A1 | |
| SCHEMBL2413130 | 0.88 | L3MBTL1 (0.33) | PTGDR2CCKARCNR1CNR2L3MBTL1 | |
| SCHEMBL2408357 | 0.88 | CTSD (0.32) | PTGDR2CCKARL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |