SCHEMBL2413232

SCHEMBL2413232

CC(=O)CC(=O)NN1CCOCC1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.45
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
SMN1; SMN2 Q16637 5/20 0.42
HTT P42858 1/20 0.40
EPHX2 P34913 1/20 0.40
LIPE Q05469 3/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8054253 0.82 CYP2D6 (0.46) CYP2D6CA12CA1CA2CA9
SCHEMBL7646012 0.82 CA12 (0.45) CYP2D6CA12CA1CA2CA9
SCHEMBL915516 0.81 L3MBTL1 (0.40) CA12CA2CA9HTTLIPE
SCHEMBL10509006 0.80 KDM4E (0.48) CYP2D6CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL6044868 0.80 CA12 (0.44) CYP2D6CA12CA1CA2CA9
SCHEMBL9551386 0.79 CA12 (0.47) CYP2D6CA12CA1CA2CA9
SCHEMBL14902206 0.79 L3MBTL1 (0.42) SMN1; SMN2HTTLIPE
SCHEMBL3422335 0.79 CA12 (0.50) CYP2D6CA12CA1CA2CA9
SCHEMBL19124539 0.78 LIPE (0.58) CYP2D6CA12CA1CA2CA9
SCHEMBL10667899 0.78 CA12 (0.53) CYP2D6CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed
US-9943498-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2018-04-17 US disclosed
EP-2549991-B1 FE(III) COMPLEX COMPOUNDS FOR TREATING AND PROPHYLAXIS FOR ANAEMIA SYMPTOMS AND ANAEMIA VIFOR (INTERNATIONAL) AG (CH) 2017-11-22 EP disclosed
EP-2549991-B1 FE(III) COMPLEX COMPOUNDS FOR TREATING AND PROPHYLAXIS FOR ANAEMIA SYMPTOMS AND ANAEMIA VIFOR (INTERNATIONAL) AG (CH) 2017-11-22 EP disclosed
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2016-10-27 US disclosed
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2016-10-27 US disclosed
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias VIFOR (INTERNATIONAL) AG (CH) 2016-10-27 US disclosed
US-9394324-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2016-07-19 US disclosed
US-9394324-B2 Fe(III) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR (INTERNATIONAL) AG (CH) 2016-07-19 US disclosed
EP-2549991-A1 FE(III) COMPLEX COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF IRON DEFICIENCY SYMPTOMS AND IRON DEFICIENCY ANEMIAS Vifor (International) AG (CH) 2013-01-30 EP disclosed
CN-102892415-A Fe(iii) complex compounds for the treatment and prophylaxis of iron deficiency symptoms and iron deficiency anemias VIFOR INT AG 2013-01-23 CN disclosed
WO-2011117225-A1 FE(III) COMPLEX COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF IRON DEFICIENCY SYMPTOMS AND IRON DEFICIENCY ANEMIAS VIFOR (INTERNATIONAL) AG (CH) 2011-09-29 WO disclosed
WO-2011117225-A1 FE(III) COMPLEX COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF IRON DEFICIENCY SYMPTOMS AND IRON DEFICIENCY ANEMIAS VIFOR (INTERNATIONAL) AG (CH) 2011-09-29 WO disclosed
EP-0924247-B2 Thermosetting resin composition and producing process thereof NIPPON CATALYTIC CHEM IND (JP) 2005-11-09 EP disclosed
EP-0924247-B1 Thermosetting resin composition and producing process thereof NIPPON CATALYTIC CHEM IND (JP) 2003-03-19 EP disclosed
US-6140396-A RESIN COMPOSITION INCLUDING N-OXYLS HAVING A SPECIFIC STRUCTURE AND A SYNTHETIC RESIN, SUCH AS A VINYL ESTER RESIN, AN URETHANE(METH)ACRYLATE RESIN, AN UNSATURATED POLYESTER RESIN, A POLYESTER(METH)ACRYLATE RESIN, AND ACRYLIC SYRUP NIPPON SHOKUBAI CO., LTD. (JP) 2000-10-31 US disclosed
EP-0924247-A1 Thermosetting resin composition and producing process thereof NIPPON SHOKUBAI CO., LTD. (JP) 1999-06-23 EP disclosed
US-4179557-A Acylation of 7-aminocephalosporanic acids PRESIDENT OF OSAKA UNIVERSITY (JP) 1979-12-18 US disclosed
US-4123611-A N-protected amino compounds PRESIDENT OF OSAKA UNIVERSITY (JP) 1978-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160310459-A1 Fe(III) Complex Compounds For The Treatment And Prophylaxis Of Iron Deficiency Symptoms And Iron Deficiency Anemias FECH, SDHB, SLC40A1 CYP2D6 774/4885CA12 673/4885CA1 2033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.