Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10094219 | 0.80 | MAPT (0.47) | MAPTEPHX2PDE2A | |
| SCHEMBL16302584 | 0.74 | ALDH1A1 (0.42) | MAPTEPHX2PDE2A | |
| SCHEMBL14232686 | 0.74 | EPHX2 (0.44) | MAPTEPHX2PDE2A | |
| SCHEMBL10138375 | 0.70 | SLC6A2 (0.38) | MAPT | |
| SCHEMBL254957 | 0.64 | MAPT (0.56) | MAPTEPHX2PDE2A | |
| SCHEMBL22793647 | 0.64 | CXCR2 (0.44) | — | |
| SCHEMBL9635559 | 0.63 | ALDH1A1 (0.48) | MAPT | |
| SCHEMBL9324441 | 0.63 | PPARA (0.45) | MAPT | |
| SCHEMBL9325496 | 0.63 | ACHE (0.46) | MAPT | |
| SCHEMBL9324454 | 0.63 | CA1 (0.55) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3928779-A1 | PHARMACEUTICAL CONTAINING SODIUM-DEPENDENT PHOSPHATE TRANSPORTER INHIBITOR AND PHOSPHORUS ADSORBENT FOR USE IN THE PREVENTION, TREATMENT OR SUPPRESSION OF CHRONIC KIDNEY DISEASE, ARTERIOSCLEROSIS ASSOCIATED WITH VASCULAR CALCIFICATION, OR ECTOPIC CALCIFICATION. | Chugai Seiyaku Kabushiki Kaisha (JP) | 2021-12-29 | — | — | EP | disclosed |