Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192366 | 0.87 | DCTPP1 (0.31) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2194609 | 0.86 | MMP2 (0.30) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2410511 | 0.86 | ABCC9 (0.33) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2412156 | 0.85 | DCTPP1 (0.32) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2409439 | 0.85 | MMP2 (0.33) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2410660 | 0.85 | — | — | |
| SCHEMBL2413757 | 0.85 | SLC6A9 (0.35) | MMP2MMP9MMP8MMP13RORC | |
| SCHEMBL2194752 | 0.84 | MMP2 (0.33) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2411039 | 0.84 | ABCC9 (0.34) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2410800 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |