Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | CCKAR | P32238 | 1/20 | 0.30 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194752 | 0.91 | MMP2 (0.33) | MMP2MMP9MMP8MMP13CYP2C9 | |
| SCHEMBL2411204 | 0.90 | ADAMTS4 (0.40) | MMP2MMP9MMP8MMP13HTR6 | |
| SCHEMBL2411039 | 0.89 | ABCC9 (0.34) | MMP2MMP9MMP8MMP13CYP2C9 | |
| SCHEMBL2192366 | 0.89 | DCTPP1 (0.31) | MMP2MMP9MMP8MMP13CYP2C9 | |
| SCHEMBL2407582 | 0.88 | MET (0.38) | MMP2MMP9MMP8MMP13CYP2C9 | |
| SCHEMBL2413757 | 0.88 | SLC6A9 (0.35) | MMP2MMP9MMP8MMP13NAMPT | |
| SCHEMBL2415904 | 0.88 | IDE (0.32) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL2408893 | 0.88 | MMP2 (0.31) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL4570000 | 0.87 | MMP2 (0.36) | MMP2MMP9MMP8MMP13NAMPT | |
| SCHEMBL2410511 | 0.87 | ABCC9 (0.33) | MMP2MMP9MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364979-A1 | Pyrrole compounds | Takeda Pharmaceutical Company Limited (JP) | 2011-09-14 | — | — | EP | disclosed |