Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24144398 | 0.77 | ADRA2A (0.38) | — | |
| SCHEMBL24143680 | 0.77 | IDO1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL22042765 | 0.75 | ADRA2A (0.39) | — | |
| Hydrochloric Acid SCHEMBL22042761 | 0.75 | IDO1 (0.32) | — | |
| SCHEMBL8975471 | 0.75 | NPC1 (0.41) | LMNA | |
| SCHEMBL1179705 | 0.72 | — | — | |
| SCHEMBL16360536 | 0.72 | LMNA (0.33) | LMNAF12 | |
| SCHEMBL795730 | 0.70 | — | — | |
| Hydrochloric Acid SCHEMBL628534 | 0.70 | P2RX7 (0.41) | LMNAF12 | |
| SCHEMBL22073074 | 0.70 | UBE2T (0.35) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105683199-B | 5-aryl-1-imino-1-oxo- [1, 2, 4] thiadiazines | 豪夫迈·罗氏有限公司 | 2018-06-26 | — | — | CN | disclosed |
| CN-105683199-A | 5-aryl-1-imino-1-oxo- [1,2,4] thiadiazines | 豪夫迈·罗氏有限公司 | 2016-06-15 | — | — | CN | disclosed |