Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 3/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PDE2A | O00408 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1507400 | 0.77 | GABRA1 (0.35) | GABRA1GABRB2ALDH1A1 | |
| SCHEMBL456893 | 0.74 | P2RX1 (0.36) | TACR1GPBAR1P2RX1 | |
| SCHEMBL3695186 | 0.73 | GABRA1 (0.34) | GABRA1GABRB2 | |
| Ether SCHEMBL4650216 | 0.70 | PDE2A (0.35) | PDE2A | |
| Benzene SCHEMBL30336225 | 0.69 | TSHR (0.43) | TACR1P2RX1ALDH1A1 | |
| SCHEMBL41567 | 0.69 | CES2 (0.44) | ALDH1A1PDE2A | |
| Aniline SCHEMBL1010731 | 0.69 | ALDH1A1 (0.43) | TACR1GABRB2P2RX1ALDH1A1 | |
| SCHEMBL29853969 | 0.68 | PDE2A (0.36) | TACR1PTPN5GABRB2ALDH1A1PDE2A | |
| SCHEMBL7458854 | 0.68 | P2RX1 (0.32) | GPBAR1P2RX1 | |
| Tert-Butylamine SCHEMBL23802681 | 0.68 | RAPGEF4 (0.37) | TACR1GABRB2ALDH1A1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1546223-A2 | SUPERCRITICAL POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREFROM | ExxonMobil Chemical Patents Inc. (US) | 2005-06-29 | — | — | EP | claimed |
| WO-2004026923-A9 | SUPERCRITICAL POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREFROM | EXXONMOBIL CHEM PATENTS INC (US) | 2004-09-10 | — | — | WO | claimed |
| WO-2004026923-A2 | SUPERCRITICAL POLYMERIZATION PROCESS AND POLYMERS PRODUCED THEREFROM | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2004-04-01 | — | — | WO | claimed |
| EP-2368896-A1 | Mono-indenyl transition metal compounds and polymerization therewith | ExxonMobil Chemical Patents Inc. (US) | 2011-09-28 | — | — | EP | disclosed |