Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.42 |
| ▸ | TLK2 | Q86UE8 | 8/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153254 | 0.89 | TLK2 (0.44) | TLK2PRKDCJAK3L3MBTL1GAA | |
| SCHEMBL24151550 | 0.87 | GAA (0.52) | TLK2PRKDCJAK3GAAPDPK1 | |
| SCHEMBL24151549 | 0.85 | RXFP1 (0.49) | NPC1RAB9ATLK2PRKDCJAK3 | |
| SCHEMBL24152343 | 0.85 | KMT2A (0.51) | NPC1RAB9ATLK2PRKDCJAK3 | |
| SCHEMBL24153211 | 0.84 | JAK3 (0.44) | TLK2PRKDCJAK3L3MBTL1GAA | |
| SCHEMBL24152344 | 0.84 | KMT2A (0.52) | NPC1RAB9ATLK2PRKDCJAK3 | |
| SCHEMBL24153266 | 0.84 | NPC1 (0.45) | NPC1RAB9APIM1PIM2GAA | |
| SCHEMBL24152342 | 0.83 | NPC1 (0.46) | NPC1RAB9APIM1PIM2GAA | |
| SCHEMBL24151582 | 0.82 | PDPK1 (0.43) | TLK2PRKDCJAK3PDPK1 | |
| SCHEMBL24152827 | 0.82 | PRKDC (0.41) | TLK2PRKDCJAK3L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |