Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 2/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | TLK2 | Q86UE8 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24151550 | 0.87 | GAA (0.52) | PDPK1PRKDCTLK2JAK3MGAT2 | |
| SCHEMBL24153254 | 0.85 | TLK2 (0.44) | PDPK1PRKDCTLK2JAK3ALDH1A1 | |
| SCHEMBL24153211 | 0.84 | JAK3 (0.44) | PDPK1PRKDCTLK2JAK3CDK2 | |
| SCHEMBL24152341 | 0.82 | NPC1 (0.46) | PDPK1PRKDCTLK2JAK3 | |
| SCHEMBL24153266 | 0.82 | NPC1 (0.45) | ALDH1A1 | |
| SCHEMBL24152342 | 0.81 | NPC1 (0.46) | ALDH1A1 | |
| SCHEMBL24152827 | 0.81 | PRKDC (0.41) | PDPK1PRKDCTLK2JAK3MGAT2 | |
| SCHEMBL24152344 | 0.81 | KMT2A (0.52) | PDPK1PRKDCTLK2JAK3MGAT2 | |
| SCHEMBL24152392 | 0.80 | MOGAT2 (0.45) | PDPK1CDK2ALDH1A1CTDSP1MGAT2 | |
| SCHEMBL24151592 | 0.78 | CDK2 (0.43) | PDPK1PRKDCTLK2JAK3CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |