Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TLK2 | Q86UE8 | 8/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 3/20 | 0.41 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153254 | 0.91 | TLK2 (0.44) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL24153211 | 0.90 | JAK3 (0.44) | GAAMEN1KMT2APOLBMAPT | |
| SCHEMBL24153266 | 0.87 | NPC1 (0.45) | GAAMEN1KMT2APOLB | |
| SCHEMBL24152341 | 0.87 | NPC1 (0.46) | GAATLK2PRKDCPDPK1JAK3 | |
| SCHEMBL24151582 | 0.87 | PDPK1 (0.43) | MAPTTLK2PRKDCPDPK1JAK3 | |
| SCHEMBL24152827 | 0.87 | PRKDC (0.41) | GAATLK2PRKDCPDPK1JAK3 | |
| SCHEMBL24152342 | 0.87 | NPC1 (0.46) | GAAPOLB | |
| SCHEMBL24152344 | 0.86 | KMT2A (0.52) | KMT2ATLK2PRKDCPDPK1JAK3 | |
| SCHEMBL24151549 | 0.85 | RXFP1 (0.49) | KMT2AMAPTTLK2PRKDCPDPK1 | |
| SCHEMBL24152340 | 0.85 | ALDH1A1 (0.43) | GAAMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |