Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153266 | 0.99 | NPC1 (0.45) | NPC1RAB9AALDH1A1PKMLMNA | |
| SCHEMBL24152340 | 0.92 | ALDH1A1 (0.43) | ALDH1A1PKMLMNAGAAPOLB | |
| SCHEMBL24151550 | 0.87 | GAA (0.52) | GAAPOLB | |
| SCHEMBL24153254 | 0.85 | TLK2 (0.44) | ALDH1A1GAAPOLB | |
| SCHEMBL24153211 | 0.84 | JAK3 (0.44) | LMNAGAAPOLB | |
| SCHEMBL24152341 | 0.83 | NPC1 (0.46) | NPC1RAB9AGAAPIM1PIM2 | |
| SCHEMBL24151582 | 0.81 | PDPK1 (0.43) | ALDH1A1 | |
| SCHEMBL24152827 | 0.81 | PRKDC (0.41) | PKMGAA | |
| SCHEMBL24152344 | 0.80 | KMT2A (0.52) | NPC1RAB9A | |
| SCHEMBL24152889 | 0.77 | CASP3 (0.59) | ALDH1A1GAAAURKAAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |