Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | PRKDC | P78527 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TLK2 | Q86UE8 | 5/20 | 0.41 |
| ▸ | MGAT2 | Q10469 | 5/20 | 0.39 |
| ▸ | PAK4 | O96013 | 3/20 | 0.39 |
| ▸ | MGAT1 | P26572 | 2/20 | 0.39 |
| ▸ | MGAT3 | Q09327 | 2/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153254 | 0.88 | TLK2 (0.44) | KMT2APRKDCTLK2JAK3PDPK1 | |
| SCHEMBL24151549 | 0.87 | RXFP1 (0.49) | KMT2APRKDCNPC1RAB9ATLK2 | |
| SCHEMBL24151550 | 0.86 | GAA (0.52) | KMT2APRKDCTLK2MGAT2JAK3 | |
| SCHEMBL24152343 | 0.85 | KMT2A (0.51) | KMT2APRKDCNPC1RAB9ATLK2 | |
| SCHEMBL24153211 | 0.85 | JAK3 (0.44) | KMT2APRKDCTLK2JAK3PDPK1 | |
| SCHEMBL24152341 | 0.84 | NPC1 (0.46) | PRKDCNPC1RAB9ATLK2JAK3 | |
| SCHEMBL24151592 | 0.83 | CDK2 (0.43) | PRKDCTLK2JAK3PDPK1 | |
| SCHEMBL24152827 | 0.82 | PRKDC (0.41) | PRKDCTLK2MGAT2MGAT1JAK3 | |
| SCHEMBL24153266 | 0.81 | NPC1 (0.45) | KMT2ANPC1RAB9A | |
| SCHEMBL24151582 | 0.81 | PDPK1 (0.43) | PRKDCTLK2MGAT2JAK3PDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |