Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 4/20 | 0.44 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | TLK2 | Q86UE8 | 7/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152827 | 0.92 | PRKDC (0.41) | JAK3PRKDCTLK2PDPK1GAA | |
| SCHEMBL24151550 | 0.90 | GAA (0.52) | JAK3PRKDCTLK2PDPK1GAA | |
| SCHEMBL24153254 | 0.88 | TLK2 (0.44) | JAK3PRKDCTLK2PDPK1GAA | |
| SCHEMBL24152344 | 0.85 | KMT2A (0.52) | JAK3PRKDCTLK2PDPK1RXFP1 | |
| SCHEMBL24153266 | 0.84 | NPC1 (0.45) | GAAMEN1POLBKMT2ALMNA | |
| SCHEMBL24152341 | 0.84 | NPC1 (0.46) | JAK3PRKDCTLK2PDPK1GAA | |
| SCHEMBL24151582 | 0.84 | PDPK1 (0.43) | JAK3PRKDCTLK2PDPK1BRD4 | |
| SCHEMBL24151549 | 0.84 | RXFP1 (0.49) | JAK3PRKDCTLK2PDPK1RXFP1 | |
| SCHEMBL24152343 | 0.84 | KMT2A (0.51) | JAK3PRKDCTLK2BRD4RXFP1 | |
| SCHEMBL24152342 | 0.84 | NPC1 (0.46) | GAAPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |