Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.43 |
| ▸ | TLK2 | Q86UE8 | 3/20 | 0.41 |
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | SYK | P43405 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.37 |
| ▸ | FCER2 | P06734 | 1/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24152474 | 0.84 | CDK2 (0.45) | CDK2KDRSRCPDPK1PRKDC | |
| SCHEMBL24151583 | 0.84 | CDK2 (0.42) | CDK2KDRTLK2SRCSYK | |
| SCHEMBL24152344 | 0.83 | KMT2A (0.52) | TLK2PDPK1PRKDCJAK3 | |
| SCHEMBL24152477 | 0.80 | SYK (0.49) | CDK2SRCSYK | |
| SCHEMBL24152348 | 0.80 | SYK (0.47) | CDK2KDRSRCSYKFCER2 | |
| SCHEMBL24151597 | 0.80 | MGAT2 (0.49) | CDK2KDRTLK2SRC | |
| SCHEMBL24152849 | 0.80 | MGAT2 (0.49) | CDK2SRCSYKPDPK1PRKDC | |
| SCHEMBL24151798 | 0.79 | SYK (0.44) | CDK2SRCSYKPDPK1 | |
| SCHEMBL24151529 | 0.78 | SYK (0.61) | TLK2SRCSYKNTRK1FCER2 | |
| SCHEMBL24151582 | 0.78 | PDPK1 (0.43) | CDK2TLK2SRCPDPK1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |