Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | PRNP | P04156 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24153262 | 0.93 | TRPA1 (0.36) | TRPA1CA1CA2SMN1; SMN2POLB | |
| SCHEMBL24151584 | 0.92 | TRPA1 (0.42) | TRPA1LMNASMN1; SMN2POLBMAPT | |
| SCHEMBL24153260 | 0.87 | TRPA1 (0.36) | TRPA1CA1CA2SMN1; SMN2POLB | |
| SCHEMBL24152367 | 0.84 | TRPA1 (0.41) | TRPA1LMNASMN1; SMN2POLBMAPT | |
| SCHEMBL24152463 | 0.82 | TRPA1 (0.41) | TRPA1LMNASMN1; SMN2POLBMAPT | |
| SCHEMBL24152375 | 0.82 | TRPA1 (0.41) | TRPA1LMNASMN1; SMN2MAPTNR1H2 | |
| SCHEMBL24151575 | 0.81 | TRPA1 (0.61) | TRPA1CA1CA2MAPT | |
| SCHEMBL24151587 | 0.81 | TRPA1 (0.42) | TRPA1LMNASMN1; SMN2POLBMAPT | |
| SCHEMBL24152377 | 0.81 | TRPA1 (0.48) | TRPA1LMNASMN1; SMN2PKMPOLB | |
| SCHEMBL24152848 | 0.80 | MAPT (0.46) | BRD4CA1CA2SMN1; SMN2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260722-A1 | DESIGN, SYNTHESIS OF NOVEL OXYINDOLE INHIBITORS OF DENV RNA DEPENDENT RNA POLYMERASE | TRANSLATIONAL HEALTH SCIENCE AND TECHNOLOGY INSTITUTE (IN) | 2021-12-30 | — | — | WO | disclosed |