Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26846516 | 0.82 | BDKRB2 (0.33) | BDKRB2 | |
| SCHEMBL24772843 | 0.81 | HTR1A (0.44) | OPRM1HTR1AHTR2A | |
| SCHEMBL24745695 | 0.81 | — | — | |
| SCHEMBL24688624 | 0.78 | HTR1A (0.38) | BDKRB2OPRM1HTR1A | |
| SCHEMBL25800650 | 0.75 | HSD11B1 (0.31) | — | |
| SCHEMBL25792492 | 0.75 | — | — | |
| SCHEMBL24773504 | 0.75 | OPRM1 (0.31) | OPRM1 | |
| SCHEMBL24744489 | 0.72 | OPRM1 (0.41) | BDKRB2OPRM1 | |
| SCHEMBL24773446 | 0.72 | — | — | |
| SCHEMBL25565531 | 0.71 | NCF1 (0.39) | BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021262587-A1 | QUATERNARY INDAZOLE GLUCOCORTICOID RECEPTOR ANTAGONISTS | CORCEPT THERAPEUTICS INCORPORATED (US) | 2021-12-30 | — | — | WO | disclosed |