SCHEMBL24154693

SCHEMBL24154693

CCOc1ccc(C2C3C=CC(CC3)N2C)cn1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACACB O00763 6/20 0.35
MAPT P10636 1/20 0.35
GPR174 Q9BXC1 1/20 0.34
AOC3 Q16853 2/20 0.32
SYK P43405 1/20 0.32
CHRNA7 P36544 1/20 0.31
IKZF2 Q9UKS7 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30116768 1.00 ACACB (0.35) ACACBMAPTGPR174AOC3SYK
SCHEMBL30116760 0.86 CHRNB2 (0.32) SLC6A2SLC6A4SLC6A3
SCHEMBL28973745 0.86 CHRNB2 (0.32) SLC6A2SLC6A4SLC6A3
SCHEMBL30116765 0.79 CHRNB2 (0.31)
SCHEMBL25861913 0.79 CHRNB2 (0.31)
SCHEMBL24154692 0.79 CHRNB2 (0.49) CHRNA7
SCHEMBL24154690 0.78 SSTR4 (0.34)
SCHEMBL24154841 0.75 GPR174 (0.38) ACACBMAPTGPR174AOC3
SCHEMBL8076992 0.71 CHRNA7 (0.46) MAPTCHRNA7
SCHEMBL30116774 0.71 CHRNA7 (0.46) MAPTCHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230225323-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL PHILIP MORRIS PRODUCTS S.A. (CH) 2023-07-20 US disclosed
US-20230225323-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL PHILIP MORRIS PRODUCTS S.A. (CH) 2023-07-20 US disclosed
CN-115698002-A Compositions and methods for parasite control 菲利普莫里斯生产公司 2023-02-03 CN disclosed
WO-2021260029-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL PHILIP MORRIS PRODUCTS S.A. (CH) 2021-12-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230225323-A1 COMPOSITIONS AND METHODS FOR PARASITE CONTROL TRHDE, CUTA, PIGS ACACB 1298/4885MAPT 243/4885GPR174 3241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.