Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP2 | P42575 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | GLP1R | P43220 | 8/20 | 0.54 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.51 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.51 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27251489 | 0.93 | SIRT1 (0.64) | CASP2FAAHGLP1RSIRT6SIRT1 | |
| SCHEMBL12431431 | 0.91 | FAAH (0.59) | CASP2FAAHGLP1RNOD1 | |
| SCHEMBL27251513 | 0.90 | EPHX2 (0.57) | CASP2FAAHGLP1RLPAR3 | |
| SCHEMBL27251493 | 0.89 | SIRT1 (0.66) | GLP1RSIRT6SIRT1 | |
| SCHEMBL27251496 | 0.89 | SIRT1 (0.66) | GLP1RSIRT6SIRT1 | |
| SCHEMBL20272601 | 0.89 | GLP1R (0.58) | CASP2FAAHGLP1RSIRT6SIRT1 | |
| SCHEMBL24155207 | 0.88 | CASP2 (0.56) | CASP2FAAHGLP1RSIRT6SIRT1 | |
| SCHEMBL17479992 | 0.88 | NOD1 (0.61) | CASP2FAAHGLP1RNAAANOD1 | |
| SCHEMBL24483387 | 0.88 | CASP2 (0.56) | CASP2FAAHGLP1RSIRT6SIRT1 | |
| SCHEMBL16221915 | 0.88 | CASP2 (0.56) | CASP2FAAHGLP1RSIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021260197-A1 | ENHANCED OLIGONUCLEOTIDES FOR MODULATING FUBP1 EXPRESSION | F. HOFFMANN-LA ROCHE AG (CH) | 2021-12-30 | — | — | WO | disclosed |