Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8762097 | 0.87 | NR4A1 (0.41) | L3MBTL1RAB9AMAPTLMNAATM | |
| SCHEMBL24155484 | 0.85 | MAPT (0.50) | L3MBTL1RAB9AMAPTLMNANPSR1 | |
| SCHEMBL8762387 | 0.85 | NR4A1 (0.58) | L3MBTL1RAB9AMAPTLMNANR4A1 | |
| SCHEMBL10924561 | 0.84 | RAB9A (0.47) | L3MBTL1RAB9AMAPTLMNAATM | |
| SCHEMBL8166370 | 0.84 | ALDH1A1 (0.47) | L3MBTL1RAB9AMAPTLMNANR4A1 | |
| SCHEMBL23530428 | 0.84 | ALDH1A1 (0.47) | L3MBTL1RAB9AMAPTLMNANR4A1 | |
| SCHEMBL486670 | 0.83 | NR4A1 (0.61) | L3MBTL1RAB9AMAPTLMNANR4A1 | |
| SCHEMBL7997269 | 0.83 | HAO1 (0.45) | L3MBTL1RAB9AMAPTLMNAATM | |
| SCHEMBL15697305 | 0.81 | AR (0.40) | L3MBTL1RAB9AMAPTLMNAATM | |
| SCHEMBL378246 | 0.81 | ALDH1A1 (0.52) | L3MBTL1RAB9AMAPTLMNAATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993014062-A1 | ANTHELMINTIC β-KETOAMIDES | THE UPJOHN COMPANY (US) | 1993-07-22 | — | — | WO | claimed |
| WO-1993014062-A1 | ANTHELMINTIC β-KETOAMIDES | THE UPJOHN COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |