Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | IKBKB | O14920 | 3/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | HPGDS | O60760 | 4/20 | 0.45 |
| ▸ | VRK1 | Q99986 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24156334 | 0.89 | MEN1 (0.52) | MEN1NPC1RAB9AKMT2AGAA | |
| SCHEMBL6032917 | 0.78 | DYRK1A (0.62) | NPC1RAB9AIKBKBDYRK1AVRK1 | |
| SCHEMBL21995555 | 0.77 | FTO (0.68) | NPC1RAB9ASMN1; SMN2HTTALKBH5 | |
| SCHEMBL8517411 | 0.77 | IKBKB (0.55) | MEN1NPC1RAB9AKMT2ASMN1; SMN2 | |
| SCHEMBL24156361 | 0.77 | MEN1 (0.58) | MEN1NPC1RAB9AKMT2AGAA | |
| SCHEMBL31214345 | 0.76 | DYRK1A (0.72) | NPC1RAB9ADYRK1AVRK1ALDH1A1 | |
| SCHEMBL24155661 | 0.73 | NPC1 (0.60) | MEN1NPC1RAB9AKMT2AGAA | |
| SCHEMBL24155536 | 0.72 | PIK3CA (0.61) | MEN1NPC1RAB9AKMT2AGAA | |
| SCHEMBL23480164 | 0.72 | DYRK1A (0.57) | NPC1RAB9AIKBKBDYRK1AVRK1 | |
| SCHEMBL2457178 | 0.72 | DYRK1A (0.54) | NPC1RAB9ADYRK1AVRK1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2021-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210403456-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY | SLC6A11, SCN1A, SCN1B | MEN1 450/4885NPC1 1298/4885RAB9A 2321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.